As GABA decreases, cognition declines.

In Aging, Brain Disorders, Brain General Structure and Function, Brain Science, Memory and Learning by Brainy Days Ahead

GABA is the primary inhibitory neurotransmitter in the brain. Now in a study by researchers at the University of Florida’s Center for Cognitive Aging and McKnight Brain Institute find an association between higher GABA concentrations in the frontal lobe, a brain region important for complex cognitive functioning, and superior performance on a cognitive test in healthy older adults. The findings illuminate the role of age-related GABA decreases¬†and suggest that declining frontal GABA concentrations may help predict neurodegenerative disease.