Autism spectrum disorder (ASD) is the fastest-growing developmental disability in the U.S., with 1 in every 68 children born in this country diagnosed with ASD. Researchers from the Mucosal Immunology and Biology Research Center at MassGeneral Hospital for Children (MGHfC) analyzed postmortem cerebral cortex and cerebellum tissues from 33 individuals – 8 with ASD, 10 with schizophrenia and 15 healthy controls. The study was driven in part by the high number of gastrointestinal problems that occur in people with ASD. The research supported the hypothesis that an impaired blood-brain barrier associated with neuroinflammation contributes to ASD. Sixty-six percent showed a higher expression of molecules that increase intestinal permeability.