Breakthrough: The young cure the old of Alzheimer’s.

In Aging, Alzheimer's, Brain Disorders, Brain Science by Brainy Days Ahead

Amyloid plaques that occur in Alzheimer’s are created by misfolded proteins that clump together and damage nerve cells. German scientists have discovered a way to remove these plaques. The scientists took aged microglia cells (scavenger cells of the brain’s immune system) and co-cultured them with microglia tissue from younger mouse brains. Within a few days, the older amyloid plaques began to resume cell division and eventually cleared the brain of plaque. The transformation is linked to a protein called “granulocyte-macrophage colony stimulating factor” (GM-CSF) that the young microglia cells were secreting.