Closing in on controlling epilepsy seizures.

In Brain Disorders, Brain Science by Brainy Days Ahead

A new direction in the treatment of epilepsy is aimed at inhibiting AMPA receptors, which help transmit electrical signals in the brain and play a key role in propagating seizures. Perampanel, which has unwanted side effects, is the only FDA-approved drug that targets AMPA receptors. In this study, the researchers were able to pinpoint exactly where the drugs bind to AMPA receptors. This knowledge may allow drug makers to develop medications that are highly selective for the AMPA receptors and therefore have fewer unwanted side effects.