Discovered protein controls schizophrenia gene.

In Brain Disorders, Brain General Structure and Function, Brain Science, DNA, Genetics by Brainy Days Ahead

The DISC1 gene is involved in nerve cell growth, signaling, and neuroplasticity (the ability of the brain to grow and adjust throughout a person’s lifetime). Impairment of DISC1 functionality can lead to schizophrenia-like symptoms. Caveolin (Cav-1) is a cell membrane protein that promotes nerve signaling and neuroplasticity in the nervous system. In this study, researchers from the University of California, San Diego looked at the interaction between Cav-1 and DISC1 in the nerve cells of mice and find that the Cav-1 protein regulates the function of DISC1. The study’s findings have significant implications for schizophrenia treatment.