Discovered protein restores degenerated brain cells.

In Aging, Alzheimer's, Brain Disorders by Brainy Days Ahead

Neurodegenerative diseases like Parkinson’s, Huntington’s, Alzheimer’s, and amyotrophic lateral sclerosis (ALS) are disorders triggered by misbehaving proteins in the brain. The proteins misfold and accumulate in neurons, inflicting damage and eventually killing the cells. Researchers at the Gladstone Institutes used a different protein, Nrf2, to restore levels of the disease-causing proteins to a normal, healthy range and thereby preventing cell death. In the study, the scientists used both rat neurons and human neurons created from induced pluripotent stem cells.