Microbiome, Brain Communication Pathway Identified.

In Brain General Structure and Function, Brain Science, Endocrine System by Brainy Days Ahead

The microbiome, comprising our collection of gut microbes, can influence human health, behavior, and certain neurological disorders, such as autism. Results from a new University of Illinois study suggest a pathway of communication between certain gut bacteria and brain metabolites, by way of a compound in the blood known as cortisol. Studying 1-month-old piglets, which have gut/brain development similar to human infants,  the researchers undertook to find bacteria in the feces of the piglets that might predict concentrations of compounds in the blood and brain, both of which are more difficult to characterize in infants. The researchers identified predictive relationships between fecal bacteria and brain metabolites and also found predictive relationships between the fecal microbiota and serotonin and cortisol, two compounds in the blood known to be influenced by gut microbiota.