Plaque Amount In Brain Predicts Cognitive Decline Over Time.

In Alzheimer's, Brain Disorders, Brain General Structure and Function, Brain Science by Brainy Days Ahead

Plaque buildup in the brain is examined using positron emission tomography (PET) scans to detect amyloid in 184 healthy middle-age and older adults participating in the Dallas Lifespan Brain Study. Researchers at The University of Texas at Dallas have found that the amount of amyloid plaques in a person’s brain predicts the rate at which his or her cognition will decline in the next four years. The study presents some of the first data on amyloid and its cognitive consequences in adults ages 40 to 59. Higher amyloid amounts were associated with declines in vocabulary, an area of cognition that is generally preserved as people age.