Tau Protein Brain Structures Seen In New High-Resolution.

In Alzheimer's, Brain Disorders, Brain Science, Brain Technology, Dementia by Brainy Days Ahead

Tau proteins are extremely important to the progression of Alzheimer’s disease and certain types of dementia. Scientists at the MRC Laboratory of Molecular Biology in the United Kingdom and Indiana University School of Medicine, in research deemed to be one of the major discoveries of the past 25 years, are the first to present high-resolution structures of tau filaments from the brain of a patient with a confirmed diagnosis of Alzheimer’s disease. Tau filaments are invisible using a the light microscope, whereas the high-resolution images obtained through the new technique called cryo-electron microscopy show their atomic structure. The researchers believe this technological breakthough has the potential for researchers to identify new strategies that will yield more effective therapeutic agents for the treatment of  neurodegenerative diseases.